Uludağ Üniversitesi Anasayfa
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Yrd. Doç. Dr. Dilek Pirim

Adı Soyadı: Dilek Pirim

Doğum Tarihi: 17/03/1985

Unvanı: Yrd. Doç. Dr.

İletişim: dilekpirim@uludag.edu.tr  

Dahili: 42835

Öğrenim Durumu:

2014 Doktora: University of Pittsburgh, Graduate School of Public Health, Department of Human Genetics, Pittsburgh, USA

2010 M.Sc: University of Pittsburgh, Graduate School of Public Health, Department of Human Genetics, Pittsburgh, USA

2007 Lisans: İstanbul Üniversitesi, Moleküler Biyoloji ve Genetik Bölümü

Akademik Unvanlar:

Yardımcı Doçent : 2016

Ödüller:
2017 Young Investigator Award, European Society of Atherosclerosis, 85th EAS Congress, Prague, Czech Republic
2015 European Society of Human Genetics Fellowship, The 4th Next Generation Sequencing Course, Bertinoro, Italy
2014 Outstanding Student Award, University of Pittsburgh, USA
2012 George Qi Wang Award in pharmacogenetics , University of Pittsburgh, USA
2007 Yüksek Öğretim Kurumları Amerika Master ve Doktora Bursu

Yayınlar
Uluslararası hakemli dergilerde yayınlanan makaleler (SCI & SSCI & Arts and Humanities)

Coban Neslihan, Pirim Dilek, Aycan Fahri Erkan, Güclü-Geyik Filiz, Ekici Berkay, Erginel-Ünaltuna Nihan. Micro-RNA-5P as a novel candidate modulators of AMPK pathway in statin-treated individuals without coronary artery disease, 2016, Deneysel Tıp Dergisi, 6, 11, 11-20

Pirim D, Wang X, Radwan ZH, Niemsiri V, Bunker CH, J.E. Hokanson, R.F. Hamman, Barmada MM, Demirci FY, Kamboh MI. Resequencing of the CETP gene in NHWs andAfrican blacks and association with lipoprotein lipid levels. Metabolism Clinical and Experimental, January 2016, Vol. 65, Issue 1, p36–47.

Pirim D, Wang X, Radwan ZH, Niemsiri V, Bunker CH, Barmada MM, Demirci FY, Kamboh MI. Resequencing of LPL in African blacks and association with lipoprotein lipid levels. Eur J Hum Genet. 2015 Jan 28

Pirim D, Wang X, Radwan ZH, Niemsiri V, Hokanson JE, Hamman RF, Barmada MM, Demirci FY, Kamboh MI. Lipoprotein lipase gene sequencing and plasma lipid profile. JLipid Res. 2014 Jan;55(1):85-93. doi: 10.1194/jlr.M043265.

Niemsiri V, Wang X, Pirim D, Radwan ZH, Hokanson JE, Hamman RF, Barmada MM, Demirci FY, Kamboh MI. Impact of Genetic Variants in Human Scavenger Receptor Class B Type I (SCARB1) on Plasma Lipid Traits. Circ Cardiovasc Genet. 2014 Sep 22. PubMed PMID: 25245032.

Z. H. Radwan, X. Wang, F. Waqar, D. Pirim, V. Niemsiri, J. E. Hokanson, R. F. Hamman, C. H. Bunker, M. M. Barmada, F. Y. Demirci, M. I. Kamboh. Comprehensive evaluation of the association of APOE genetic variation with plasma lipoprotein traits in U.S. Whites and African Blacks PLoS One. 2014 Dec 12;9(12):e114618. doi:10.1371/journal.pone.0114618.

V. Niemsiri, X. Wang, D. Pirim, Z. H. Radwan, C. H. Bunker, M. Michael Barmada, F.Yesim Demirci, M. Ilyas Kamboh. Genetic contribution of SCARB1 variants to lipid traits in African Blacks: a candidate gene association study. BMC Med Genet. 2015 Nov 12;16(1):106.

Uluslararası bilimsel toplantılarda sunulan ve bildiri kitabında (Proceedings) basılan bildiriler
Dilek Pirim, Zaheda H. Radwan, Xingbin Wang,, Fahad Waqar, Vipavee Niemsiri, John E. Hokanson, Richard F. Hamman, Clareann H. Bunker, M. Michael Barmada, Eleanor Feingold, F. Yesim Demirci, M. Ilyas Kamboh, A Comprehensive association study of apolipoprotein E-C1-C4-C2 gene cluster variation with plasma lipoprotein traits, 85th European Atherosclerosis Society Congress, April 23-26 2017. Prague, Czech Republic,

N. Coban, D. Pirim, A. F. Erkan, F. Güçlü-Geyik, B. Ekici, N. Erginel-Unaltuna Plasma levels of miR-19a, miR-26a and miR-584 are associated with severity of coronary artery disease in Turkish men. 705F. Annual American Society of Human Genetics Congress, October 18-22 2016, Vancouver, USA

N. Coban, D. Pirim, A. F. Erkan, F. Güçlü-Geyik, B. Ekici, N. Erginel-Unaltuna. MicroRNA- 625-5p as a novel candidate modulator of AMPK pathway in statintreated individuals without coronary artery disease. European Human Genetics Conference, May 21-24 2016, Barcelona, Spain.

V. Niemsiri, X. Wang, Z. H. Radwan, D. Pirim, J. E. Hokanson, R. F. Hamman, M. M. Barmada, F. Y. Demirci, M. I. Kamboh. The contribution of common and lowfrequency/rare  variants in ATP-binding cassette A1 (ABCA1) to lipoprotein-lipid traits. Annual American Society of Human Genetics Congress, October 6-10 2015, Baltimore, USA.

D. Pirim, Xingbin Wang, John E. Hokanson, Richard F. Hamman, M. Michael Barmada, F. Yesim Demirci, M. Ilyas Kamboh CETP gene variation and its association with plasma lipoprotein-lipid traits in U.S. Whites. 2013 XIII. National Congress of Medical Biology and Genetics, Kusadasi, Aydin, Turkiye. Abstract: 0327

D. Pirim, F.Y. Demirci, X. Wang, J.E. Hokanson, R.F. Hamman, C.H. Bunker, M.M. Barmada, M.I. Kamboh. Identification of sequence variants of hepatic lipase (LIPC) gene in individuals with extreme HDL-C/TG levels. Presented at the 63rd Annual Meeting of The American Society of Human Genetics, October 23, 2013 in Boston, MA

D. Pirim, F Y Demirci, X. Wang, M Irfan, Y. Wang, JE Hokanson, RF Hamman, M Kammerer, and MI Kamboh Resequencing of the Lipoprotein Lipase Gene in Individuals with Extreme HDL-Cholesterol Levels Arterioscler Thromb Vasc Biol. 2012; 32: A324. Presented at the ATVB meeting, April 19th, 2012 in Chicago,Illinois.

D. Pirim, F. Y. Demirci, X. Wang, J. E. Hokanson, R. F. Hamman, C. H. Bunker, C. M. Kammerer, M. M. Barmada, M. I. Kamboh. Resequencing of the Cholesteryl Ester Transfer Protein gene (CETP) in U.S. Whites and African Blacks with extreme HDL-C levels. Presented at the 62nd Annual Meeting of The American Society of Human Genetics. November 7, 2012 in San Francisco, California

D. Pirim, F. Y. Demirci, S. C. Hughes, M. Irfan, Y. Wang, J. E. Hokanson, R. F. Hamman, C.M. Kammerer, M. I. Kamboh. Lipoprotein lipase gene (LPL) resequencing and plasma lipid profile. Presented at the 12th International Congress of Human Genetics/61st Annual Meeting of The American Society of Human Genetics, October 12, 2011, Montreal, Canada

Projeler

Araştırmacı, Seramid metabolizması ile ilişkili miRNA'ların koroner arter hastalığı üzerine etkisinin araştırılması, 2015- 2016, İstanbul Üniversitesi BAP No: 54665
Araştırmacı, Aterosklerotik Koroner Arter Hastalığı’nın Anjiografik Yaygınlık ve Ciddiyet Derecesi Üzerine Genetik Araştırma, 2014-2017, İstanbul Üniversitesi BAP No: 47372

Bilimsel ve Mesleki Kuruluşlara Üyelikler

Euoropean Society of Atherosclerosis
American Society of Human Genetics

Editörlük ve Hakemlikler
Global Journal of Health Science, Editorial board member
Austin Public Health, Editorial board member
Epigenetic Diagnosis & Therapy, Editorial board member
Journal of Genomics and Bioinformatics, Review Board member